BDBM50212688 2-(3,5-dimethyl-benzyl)-5-trifluoromethoxy-2,3-dihydro-isoindol-1-ylideneamine::CHEMBL429656

SMILES Cc1cc(C)cc(CN2Cc3cc(OC(F)(F)F)ccc3C2=N)c1

InChI Key InChIKey=XGUYIUIDDDYQNH-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50212688   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212688(2-(3,5-dimethyl-benzyl)-5-trifluoromethoxy-2,3-dih...)
Affinity DataKi:  2nMAssay Description:Binding affinity to NMDA NR2B receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212688(2-(3,5-dimethyl-benzyl)-5-trifluoromethoxy-2,3-dih...)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at NMDA NR2B receptor assessed as calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed