BDBM50213331 2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)methylthio)-1H-indol-1-yl)acetic acid::CHEMBL231690

SMILES Cc1nc(sc1CSc1ccc2n(CC(O)=O)ccc2c1)C(F)(F)F

InChI Key InChIKey=SBRYXHXGTIWXKI-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50213331   

TargetPeroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213331(2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]5-(4-(3-(5-methyl-2-phenyloxazol-4-yl)propanoyl)benzyl)thiazolidine-2,4-dione from human PPARgamma after 2 hrs by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213331(2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human PPARdelta in HepG2 cells by GAL4-luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213331(2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...)
Affinity DataIC50:  172nMAssay Description:Displacement of [3H]2-(4-(2-(3-(2,4-difluorophenyl)-1-heptylureido)ethyl)phenoxy)-2-methylbutanoic acid from human PPARalpha after 30 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPeroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50213331(2-(5-((4-methyl-2-(trifluoromethyl)thiazol-5-yl)me...)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [3H]2-(4-(3-(4-acetyl-3-hydroxy-2 propyl-phenoxy)propoxy)phenoxy)acetic acid from human PPARdelta after 30 mins by SPAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed