BDBM50214090 5-(4-hydroxyphenyl)-6-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one::CHEMBL248209

SMILES Cc1nc2n(ncc2c(=O)n1-c1ccc(O)cc1)-c1ccccc1

InChI Key InChIKey=RHMPXPSEUXKQBG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50214090   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214090(5-(4-hydroxyphenyl)-6-methyl-1-phenyl-1H-pyrazolo[...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at human mGluR5 receptor expressed in 132N1 cells assessed as inhibition of glutamate-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214090(5-(4-hydroxyphenyl)-6-methyl-1-phenyl-1H-pyrazolo[...)
Affinity DataIC50:  2.40E+3nMAssay Description:Antagonist activity at human mGluR1 receptor expressed in 132N1 cells assessed as inhibition of glutamate-induced calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed