BDBM50214705 5-(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)-1,1-difluoropentylphosphonate::9-(5',5'-difluoro-5'-phosphonopentyl)guanine::9-(5,5-DIFLUORO-5-PHOSPHONOPENTYL)GUANINE::CHEMBL236708::[5-(2-Amino-6-oxo-1,6-dihydro-purin-9-yl)-1,1-difluoro-pentyl]-phosphonic acid

SMILES: c1nc2c(n1CCCCC(F)(F)P(=O)(O)O)N=C(NC2=O)N

InChI Key: InChIKey=JANQQPWTLXUSCD-UHFFFAOYSA-N

Data: 6 KI  6 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50214705   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
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Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20.2	n/a	n/a	n/a	n/a	n/a	n/a
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Purine nucleoside phosphorylase (Bovine)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.7	n/a	n/a	n/a	n/a	n/a	n/a
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Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bovine)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18.7	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20.2	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bovine)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	0.460	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bovine)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Bovine)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Purine nucleoside phosphorylase (Bovine)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		10.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Human)	BDBM50214705 (9-(5',5'-difluoro-5'-phosphonopentyl)guanine | [5-...) Show SMILES Show InChI	GoogleScholar	UniChem		53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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