BDBM50214864 3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1H-imidazol-2-yl)methylamino)benzamide::CHEMBL229599

SMILES Cc1cccc(n1)-c1nc(CNc2cccc(c2)C(N)=O)[nH]c1-c1ccc2nccnc2c1

InChI Key InChIKey=YLBQHEDWGXARHK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214864   

TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50214864(3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant ALK5 phosphorylation expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50214864(3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Ewha Womans University

Curated by ChEMBL
LigandPNGBDBM50214864(3-((5-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)-1...)
Affinity DataIC50: 10nMAssay Description:Antagonistic activity at TGFBR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed