BDBM50214872 5,6,7-trihydroxy-8-isobutyl-2-methyl-3-phenyl-chromen-4-one::CHEMBL389660

SMILES CC(C)Cc1c(O)c(O)c(O)c2c1oc(C)c(-c1ccccc1)c2=O

InChI Key InChIKey=VOKVHQWUUIPROY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214872   

TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50214872(5,6,7-trihydroxy-8-isobutyl-2-methyl-3-phenyl-chro...)
Affinity DataKi:  340nMAssay Description:Displacement of FAM-Bim peptide from human Bcl2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50214872(5,6,7-trihydroxy-8-isobutyl-2-methyl-3-phenyl-chro...)
Affinity DataKi:  400nMAssay Description:Binding affinity to Mcl-1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
Dalian University Of Technology

Curated by ChEMBL
LigandPNGBDBM50214872(5,6,7-trihydroxy-8-isobutyl-2-methyl-3-phenyl-chro...)
Affinity DataKi:  400nMAssay Description:Displacement of FAM-Bim peptide from human Mcl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed