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BDBM50214914 2-(3-((benzo[d]oxazol-2-yl(3-(2,4-dimethylphenoxy)propyl)amino)methyl)phenoxy)butanoic acid::CHEMBL427701

SMILES: CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2C)c2nc3ccccc3o2)c1)C(O)=O

InChI Key: InChIKey=NPCOVXRHNOWSPC-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50214914   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peroxisome proliferator-activated receptor delta (PPAR delta)


(Homo sapiens (Human))
BDBM50214914
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2C)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-25(28(32)33)35-23-10-7-9-22(18-23)19-31(29-30-24-11-5-6-12-27(24)36-29)15-8-16-34-26-14-13-20(2)17-21(26)3/h5-7,9-14,17-18,25H,4,8,15-16,19H2,1-3H3,(H,32,33)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 110n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARdelta by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)

More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor


(Homo sapiens (human))
BDBM50214914
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2C)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-25(28(32)33)35-23-10-7-9-22(18-23)19-31(29-30-24-11-5-6-12-27(24)36-29)15-8-16-34-26-14-13-20(2)17-21(26)3/h5-7,9-14,17-18,25H,4,8,15-16,19H2,1-3H3,(H,32,33)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 130n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARgamma by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)

More data for this
Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (PPAR alpha)


(Homo sapiens (Human))
BDBM50214914
PNG
(2-(3-((benzo[d]oxazol-2-yl(3-(2,4-dimethylphenoxy)...)
Show SMILES CCC(Oc1cccc(CN(CCCOc2ccc(C)cc2C)c2nc3ccccc3o2)c1)C(O)=O
Show InChI InChI=1S/C29H32N2O5/c1-4-25(28(32)33)35-23-10-7-9-22(18-23)19-31(29-30-24-11-5-6-12-27(24)36-29)15-8-16-34-26-14-13-20(2)17-21(26)3/h5-7,9-14,17-18,25H,4,8,15-16,19H2,1-3H3,(H,32,33)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 1n/an/an/an/a



Kowa Co.

Curated by ChEMBL


Assay Description
Agonist activity at human recombinant PPARalpha by GAL4 transactivation assay


Bioorg Med Chem Lett 17: 4689-93 (2007)

More data for this
Ligand-Target Pair