BDBM50214969 1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2-enyl)-xanthen-9-one::1,3,6-trihydroxy-7-methoxy-2,8-bis(3-methylbut-2-enyl)-9H-xanthen-9-one::1,3,6-trihydroxy-7-methoxy-2,8-diprenylxanthone::CHEMBL323197::Mangostin::alpha-mangostin

SMILES: [#6]-[#8]-c1c(-[#8])cc2oc3cc(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c3c(=O)c2c1-[#6]\[#6]=[#6](\[#6])-[#6]

InChI Key: InChIKey=MJVPROLIBBFFFH-UHFFFAOYSA-N

Data: 4 KI  27 IC50  3 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 35 hits for monomerid = 50214969   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sialidase (Clostridium perfringens)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
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3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [1-175] (Yersinia pestis)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	7.0	25
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Solute carrier family 22 member 12 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Stimulator of interferon genes protein (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.37E+5	n/a	n/a	n/a	n/a	n/a
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NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Sphingomyelin phosphodiesterase (Bovine)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear factor NF-kappa-B p105 subunit (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Transcription factor p65 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.59E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid synthase (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription factor p65 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX15 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid lipoxygenase ALOX12 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	580	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Sphingomyelin phosphodiesterase 2 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.14E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sphingomyelin phosphodiesterase [1-45,48-631] (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ (Francisella tularensis)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	7.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingomyelin phosphodiesterase (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingomyelin phosphodiesterase (Bovine)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Probable maltase-glucoamylase 2 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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MAP/microtubule affinity-regulating kinase 4 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Oxidized purine nucleoside triphosphate hydrolase (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Mouse)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.37E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingomyelin phosphodiesterase (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Phosphoglycerate mutase 1 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Stimulator of interferon genes protein (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.57E+5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingomyelin phosphodiesterase (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Isocitrate dehydrogenase [NADP] cytoplasmic (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		2.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sialidase (Clostridium perfringens)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Probable maltase-glucoamylase 2 (Human)	BDBM50214969 (Mangostin | alpha-mangostin | 1,3,6-Trihydroxy-7-m...) Show SMILES Show InChI	GoogleScholar	UniChem		7.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair