BDBM50215798 CHEMBL395700::N-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-2-((2-(3-hydroxypropylamino)pyridin-4-yl)methylamino)benzamide

SMILES OCCCNc1cc(CNc2ccccc2C(=O)Nc2ccc3OC(F)(F)Oc3c2)ccn1

InChI Key InChIKey=IHZBPVIBWDITMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215798   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215798(CHEMBL395700 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant cKit by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50215798(CHEMBL395700 | N-(2,2-difluorobenzo[d][1,3]dioxol-...)
Affinity DataIC50:  142nMAssay Description:Inhibition of b-RafMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed