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BDBM50215869 CHEMBL301781

SMILES: O[C@@H]1[C@@H](Cc2ccc(F)cc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O

InChI Key: InChIKey=TVTQKPUMYOYZPC-OYHNWAKOSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50215869   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50215869
PNG
(CHEMBL301781)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(F)cc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O
Show InChI InChI=1S/C23H18ClFO4/c24-16-4-8-18(23(27)28)20(11-16)14-3-7-19-21(10-14)29-12-15(22(19)26)9-13-1-5-17(25)6-2-13/h1-8,10-11,15,22,26H,9,12H2,(H,27,28)/t15-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 54n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


Article DOI: 10.1016/s0960-894x(98)00275-3
BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair
Leukotriene B4 receptor


(Homo sapiens (Human))
BDBM50215869
PNG
(CHEMBL301781)
Show SMILES O[C@@H]1[C@@H](Cc2ccc(F)cc2)COc2cc(ccc12)-c1cc(Cl)ccc1C(O)=O
Show InChI InChI=1S/C23H18ClFO4/c24-16-4-8-18(23(27)28)20(11-16)14-3-7-19-21(10-14)29-12-15(22(19)26)9-13-1-5-17(25)6-2-13/h1-8,10-11,15,22,26H,9,12H2,(H,27,28)/t15-,22+/m0/s1
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 400n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.


Bioorg Med Chem Lett 8: 1781-6 (1998)


Article DOI: 10.1016/s0960-894x(98)00275-3
BindingDB Entry DOI: 10.7270/Q2RR21F1
More data for this
Ligand-Target Pair