BDBM50216054 1-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)indolin-2-one::CHEMBL239917

SMILES Clc1ccc(cc1)N1CCN(CCCCN2C(=O)Cc3ccccc23)CC1

InChI Key InChIKey=AEVXOGLKVVRZCX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50216054   

TargetD(1B) dopamine receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50216054(1-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)indol...)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]SCH 23390 from human Dopamine D5 receptor expressed in HEK293More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50216054(1-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)indol...)
Affinity DataKi:  375nMAssay Description:Antagonist activity at human Dopamine receptor D2 isoform long expressed in HEK293 cells assessed as change in quinpirole-induced intracellular calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50216054(1-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)indol...)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]spiperone from human Dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Cairo University

Curated by ChEMBL
LigandPNGBDBM50216054(1-(4-(4-(4-chlorophenyl)-1-piperazinyl)butyl)indol...)
Affinity DataKi:  1.75E+3nMAssay Description:Displacement of [3H]Spiperone from human Dopamine receptor D2 isoform long expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed