BDBM50216172 (Dichloro-phosphono-methyl)-phosphonic acid::CHEMBL12318::bisphosphonate clodronate::clodronic acid

SMILES OP(O)(=O)C(Cl)(Cl)P(O)(O)=O

InChI Key InChIKey=ACSIXWWBWUQEHA-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50216172   

TargetType IV secretion-like conjugative transfer relaxase protein TraI(Escherichia coli (strain SMS-3-5 / SECEC))
University Of North Carolina

Curated by ChEMBL
LigandPNGBDBM50216172((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)
Affinity DataKi:  3nMAssay Description:Inhibition of Escherichia coli F plasmid TraI relaxase Y16F mutant assessed as oriT ssDNA cleavage by competitive inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50216172((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)
Affinity DataIC50:  3.00E+5nMAssay Description:Inhibition of human recombinant MMP3 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50216172((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)
Affinity DataIC50:  1.21E+5nMAssay Description:Inhibition of human recombinant MMP12 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50216172((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)
Affinity DataIC50:  3.20E+5nMAssay Description:Inhibition of human recombinant MMP9 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Università

Curated by ChEMBL
LigandPNGBDBM50216172((Dichloro-phosphono-methyl)-phosphonic acid | CHEM...)
Affinity DataIC50:  1.45E+5nMAssay Description:Inhibition of human recombinant MMP2 after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed