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BDBM50216202 CHEMBL233797::N-(2-chlorophenethyl)-4-(piperidin-1-ylmethyl)-N-(tetrahydrofuran-3-yl)benzamide

SMILES: Clc1ccccc1CCN(C1CCOC1)C(=O)c1ccc(CN2CCCCC2)cc1

InChI Key: InChIKey=JFFXOTJSGWCHKR-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216202   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Membrane-bound transcription factor site-1 protease


(Homo sapiens (Human))
BDBM50216202
PNG
(CHEMBL233797 | N-(2-chlorophenethyl)-4-(piperidin-...)
Show SMILES Clc1ccccc1CCN(C1CCOC1)C(=O)c1ccc(CN2CCCCC2)cc1
Show InChI InChI=1/C25H31ClN2O2/c26-24-7-3-2-6-21(24)12-16-28(23-13-17-30-19-23)25(29)22-10-8-20(9-11-22)18-27-14-4-1-5-15-27/h2-3,6-11,23H,1,4-5,12-19H2
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KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human S1P expressed in CHOK1 cells


Bioorg Med Chem Lett 17: 4411-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.031
BindingDB Entry DOI: 10.7270/Q26M36JG
More data for this
Ligand-Target Pair