BDBM50216297 6',7',10,11-tetramethoxyemetan::CHEMBL50588::Emetin::Emetine::cephaeline methyl ether::methyl cephaeline

SMILES: CC[C@H]1CN2CCc3cc(c(cc3[C@@H]2C[C@@H]1C[C@@H]4c5cc(c(cc5CCN4)OC)OC)OC)OC

InChI Key: InChIKey=AUVVAXYIELKVAI-UHFFFAOYSA-N

Data: 18 IC50  2 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 20 hits for monomerid = 50216297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (ZIKV)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.70	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.07E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-dependent translocase ABCB1 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine hydrolase RBBP9 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 2 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Genome polyprotein (ZIKV)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	53	n/a	n/a	n/a	n/a
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Integrin alpha-L (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.04E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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Endothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (fumarate) (Leishmania major)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Dihydroorotate dehydrogenase (fumarate) (Leishmania major)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.07E+6	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 4 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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ATP-binding cassette sub-family C member 3 (Human)	BDBM50216297 (6',7',10,11-tetramethoxyemetan | Emetin | Emetine ...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.33E+5	n/a	n/a	n/a	n/a	n/a	n/a
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