BDBM50216434 CHEMBL245686::dimethyl-(tetrahydro-pyran-4-yl)-{4-[(E)-3-(4'-trifluoromethyl-biphenyl-4-yl)-acryloylamino]-benzyl}-ammonium

SMILES C[N+](C)(Cc1ccc(NC(=O)\C=C\c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)cc1)C1CCOCC1

InChI Key InChIKey=NLDVDIXLYWOKRA-FRKPEAEDSA-O

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216434   

TargetC-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50216434(CHEMBL245686 | dimethyl-(tetrahydro-pyran-4-yl)-{4...)
Affinity DataIC50:  10nMAssay Description:Displacement of [125I]MCP1 from CCR2 receptor expressed in THP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed