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BDBM50216605 5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)cyclopentyl)benzo[b]thiophene-2-carboxamide::CHEMBL232109

SMILES: Clc1ccc2sc(cc2c1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=RNIWMGGVQYOYAF-LEWJYISDSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216605   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50216605
PNG
(5-chloro-N-((1R,2S)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Show SMILES Clc1ccc2sc(cc2c1)C(=O)N[C@@H]1CCC[C@@H]1NC(=O)c1ccc(cc1)-n1ccccc1=O
Show InChI InChI=1S/C26H22ClN3O3S/c27-18-9-12-22-17(14-18)15-23(34-22)26(33)29-21-5-3-4-20(21)28-25(32)16-7-10-19(11-8-16)30-13-2-1-6-24(30)31/h1-2,6-15,20-21H,3-5H2,(H,28,32)(H,29,33)/t20-,21+/m0/s1
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Similars

Article
PubMed
288n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Company

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 4419-27 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.029
BindingDB Entry DOI: 10.7270/Q2416XVV
More data for this
Ligand-Target Pair