BDBM50217462 CHEMBL397693::trans-1-adamantan-1-yl-3-[4-(2,6-difluoro-4-isopropoxybenzyloxy)cyclohexyl]urea

SMILES CC(C)Oc1cc(F)c(CO[C@H]2CC[C@@H](CC2)NC(=O)NC23CC4CC(CC(C4)C2)C3)c(F)c1

InChI Key InChIKey=AHBBUWVOFCIJOB-GIYPUSOKSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50217462   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50217462(CHEMBL397693 | trans-1-adamantan-1-yl-3-[4-(2,6-di...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase using CMNPC as substrate assessed as appearance of 6-methoxy-2-naphthaldehyde after 10 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Colorado State University

Curated by ChEMBL
LigandPNGBDBM50217462(CHEMBL397693 | trans-1-adamantan-1-yl-3-[4-(2,6-di...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed