BDBM50218035 8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-yloxy)ethyl)piperazin-1-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL247428

SMILES CN1C(=O)COc2c(F)cc(CN3CCN(CCOc4cccc5nc(C)ccc45)CC3)cc12

InChI Key InChIKey=NHWFUZYIOHEXGN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50218035   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50218035(8-fluoro-4-methyl-6-((4-(2-(2-methylquinolin-5-ylo...)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed