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BDBM50218289 5-chloro-N-((1S,2R)-2-(4-(2-oxopyridin-1(2H)-yl)benzamido)-2,3-dihydro-1H-inden-1-yl)thiophene-2-carboxamide::CHEMBL236439

SMILES: Clc1ccc(s1)C(=O)N[C@@H]1[C@@H](Cc2ccccc12)NC(=O)c1ccc(cc1)-n1ccccc1=O

InChI Key: InChIKey=OGJPWEIXFUNYHQ-YKSBVNFPSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218289   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Coagulation factor X


(Homo sapiens (Human))
BDBM50218289
PNG
(5-chloro-N-((1S,2R)-2-(4-(2-oxopyridin-1(2H)-yl)be...)
Show SMILES Clc1ccc(s1)C(=O)N[C@@H]1[C@@H](Cc2ccccc12)NC(=O)c1ccc(cc1)-n1ccccc1=O
Show InChI InChI=1S/C26H20ClN3O3S/c27-22-13-12-21(34-22)26(33)29-24-19-6-2-1-5-17(19)15-20(24)28-25(32)16-8-10-18(11-9-16)30-14-4-3-7-23(30)31/h1-14,20,24H,15H2,(H,28,32)(H,29,33)/t20-,24+/m1/s1
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Similars

Article
PubMed
230n/an/an/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
Inhibition of human factor 10a


Bioorg Med Chem Lett 17: 5041-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.020
BindingDB Entry DOI: 10.7270/Q23J3CPQ
More data for this
Ligand-Target Pair