BDBM50218583 CHEMBL81364

SMILES [#6]-[#6]-[#6](-[#6])-[#6](-[#7]-[#6](=O)-[#6](-[#8])-[#6]-c1ccc(-[#8])c(Cl)c1)-[#6](=O)-[#7]-1-[#6]-2-[#6]-[#6](-[#6]-[#6]-[#6]-2-[#6]-[#6]-1-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#8]S([#8])(=O)=O

InChI Key InChIKey=LNRXFFGKAKWQCV-UHFFFAOYSA-N

Data  1 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50218583   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataKi:  383nMAssay Description:Inhibition of rolipram binding to PDE4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  870nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  240nMAssay Description:Inhibitory concentration against phosphodiesterase 4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  241nMAssay Description:In vitro inhibitory concentration against phosphodiesterase 4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ernst-Moritz-Arndt-University

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of human VCAM and Ramos cell VLA-4 interactionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Zambon Group

Curated by ChEMBL
LigandPNGBDBM50218583(CHEMBL81364)
Affinity DataIC50:  241nMAssay Description:Inhibition of human VCAM binding to VLA-4 of Ramos cells in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed