BDBM50218682 CHEMBL243575::N-[2-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-benzo[b]thiophen-7-yl]-6-cyclopropylamino-nicotinamide

SMILES COc1c(NC(=O)c2cc3cccc(NC(=O)c4ccc(NC5CC5)nc4)c3s2)cc(cc1NS(C)(=O)=O)C(C)(C)C

InChI Key InChIKey=SYLXLRJHNPOSFK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50218682   

TargetMitogen-activated protein kinase 9(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50218682(N-[2-(5-tert-butyl-3-methanesulfonylamino-2-methox...)
Affinity DataIC50: 16nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lyn(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50218682(N-[2-(5-tert-butyl-3-methanesulfonylamino-2-methox...)
Affinity DataIC50: 230nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed