BDBM7393 3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2-ylidene]-2,3-dihydro-1H-indol-2-one::CHEMBL397695::Indirubin-3 -monoxime::Indirubin-3-monoxime::Indirubin-3monoxime::indirubin deriv. 7h

SMILES: O=Nc1c([nH]c2ccccc12)C1C(=O)Nc2ccccc12

InChI Key: InChIKey=HOQNHSNBIIJJBO-UHFFFAOYSA-N

Data: 4 KI  9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 7393   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	7.2	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 [99-307] (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Porcine)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [538-972] ()	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [538-678,753-922] (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Macrophage colony-stimulating factor 1 receptor [538-678,753-922] (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	7.5	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ninein (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Sgk1 (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2 (Human)	BDBM7393 (Indirubin-3 -monoxime | 3-[(2Z,3E)-3-(hydroxyimino...) Show SMILES Show InChI	GoogleScholar	UniChem		590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair