BDBM7401 (2 Z,3 E)-6-Bromoindirubin-3 -oxime::(3E)-6-bromo-3-[3-(hydroxyamino)indol-2-ylidene]oxindole::6-bromo-3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2-ylidene]-2,3-dihydro-1H-indol-2-one::6-bromoindirubin-3 -oxime::6BIO::CHEMBL409450::indirubin deriv. 7a

SMILES: Brc1ccc2C(C(=O)Nc2c1)c1[nH]c2ccccc2c1N=O

InChI Key: InChIKey=OLOJSTRISMGUEK-UHFFFAOYSA-N

Data: 24 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 25 hits for monomerid = 7401   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Interferon-induced, double-stranded RNA-activated protein kinase (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 5 activator 1 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Rat)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	520	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase CLK1 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 5 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Pig)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform alpha (Pig)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Rat)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity tyrosine-phosphorylation-regulated kinase 2 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B1/G2/mitotic-specific cyclin-B2/G2/mitotic-specific cyclin-B3 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Glycogen synthase kinase-3 alpha (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 5 activator 1 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B (Spiny starfish)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	7.2	30
TBA									Citation and Details
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Cyclin-dependent kinase 5 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.5	30
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C-C chemokine receptor type 6 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>6.66E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-galactosidase (Escherichia coli)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sentrin-specific protease 6 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Sentrin-specific protease 8 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Caspase-3 (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Streptokinase A (Streptococcus pyogenes M1 GAS)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.49E+4	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Porcine)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
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Cyclin-dependent kinase 5 activator 1 [99-307] (Human)	BDBM7401 (6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	30
TBA									Citation and Details
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