BDBM50218973 CHEMBL44001
SMILES CC1(C)OC(=C(C1=O)c1cccc(F)c1)c1ccc(cc1)S(C)(=O)=O
InChI Key InChIKey=SLDVCDFNTJZEEB-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50218973
Affinity DataIC50: 1.38E+4nMAssay Description:Ability to inhibit Prostaglandin G/H synthase 1 by using freshly harvested mouse peritoneal macrophagesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Pacific Corporation R & D Center
Curated by ChEMBL
Pacific Corporation R & D Center
Curated by ChEMBL
Affinity DataIC50: 55.5nMAssay Description:Ability to inhibit Prostaglandin G/H synthase 2 by using freshly harvested mouse peritoneal macrophagesMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Pacific Corporation R & D Center
Curated by ChEMBL
Pacific Corporation R & D Center
Curated by ChEMBL
Affinity DataIC50: 8.32nMAssay Description:Inhibition of mouse COX-2 in LPS-induced mouse peritoneal macrophage assessed as reduction in PGE2 release incubated for 2 hrs by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.38E+4nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 1 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Pacific Corporation R & D Center
Curated by ChEMBL
Pacific Corporation R & D Center
Curated by ChEMBL
Affinity DataIC50: 55.5nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 using mouse peritoneal macrophage methodMore data for this Ligand-Target Pair