BDBM50219451 3-chloro-5-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl)benzonitrile::CHEMBL235689

SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc(Cl)cc(c1)C#N)C(F)(F)F

InChI Key InChIKey=UPKAUNVEGRFAII-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219451   

TargetMineralocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219451(3-chloro-5-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy...)
Affinity DataIC50:  730nMAssay Description:Displacement of TAMRA labeled mifepristone at human mineralocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219451(3-chloro-5-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy...)
Affinity DataIC50: >2.00E+3nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human progesterone receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50219451(3-chloro-5-(4-(5-fluoro-2-methoxyphenyl)-2-hydroxy...)
Affinity DataIC50:  27nMAssay Description:Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed