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BDBM50219461 2-benzyl-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphenyl)-4-methylpentan-2-ol::CHEMBL400628

SMILES: COc1ccc(F)cc1C(C)(C)CC(O)(Cc1ccccc1)C(F)(F)F

InChI Key: InChIKey=GODVLDDDFMZIIA-UHFFFAOYNA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50219461   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mineralocorticoid receptor


(Homo sapiens (Human))
BDBM50219461
PNG
(2-benzyl-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphen...)
Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1ccccc1)C(F)(F)F
Show InChI InChI=1/C20H22F4O2/c1-18(2,16-11-15(21)9-10-17(16)26-3)13-19(25,20(22,23)24)12-14-7-5-4-6-8-14/h4-11,25H,12-13H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.30E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Displacement of TAMRA labeled mifepristone at human mineralocorticoid receptor in insect cell


Bioorg Med Chem Lett 17: 5025-31 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.031
BindingDB Entry DOI: 10.7270/Q2G73FJ2
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))
BDBM50219461
PNG
(2-benzyl-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphen...)
Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1ccccc1)C(F)(F)F
Show InChI InChI=1/C20H22F4O2/c1-18(2,16-11-15(21)9-10-17(16)26-3)13-19(25,20(22,23)24)12-14-7-5-4-6-8-14/h4-11,25H,12-13H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 610n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Displacement of TAMRA labeled Dexamethasone at human glucocorticoid receptor in insect cell


Bioorg Med Chem Lett 17: 5025-31 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.031
BindingDB Entry DOI: 10.7270/Q2G73FJ2
More data for this
Ligand-Target Pair
Progesterone receptor


(Homo sapiens (Human))
BDBM50219461
PNG
(2-benzyl-1,1,1-trifluoro-4-(5-fluoro-2-methoxyphen...)
Show SMILES COc1ccc(F)cc1C(C)(C)CC(O)(Cc1ccccc1)C(F)(F)F
Show InChI InChI=1/C20H22F4O2/c1-18(2,16-11-15(21)9-10-17(16)26-3)13-19(25,20(22,23)24)12-14-7-5-4-6-8-14/h4-11,25H,12-13H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a>1.60E+3n/an/an/an/an/an/a



Boehringer Ingelheim Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Displacement of TAMRA labeled Dexamethasone at human progesterone receptor in insect cell


Bioorg Med Chem Lett 17: 5025-31 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.031
BindingDB Entry DOI: 10.7270/Q2G73FJ2
More data for this
Ligand-Target Pair