BDBM50219646 CHEMBL247644::N-(4-(2,3-difluoro-4-(trifluoromethyl)phenyl)thiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide

SMILES Fc1c(F)c(ccc1-c1csc(NC(=O)c2ccc(Nc3ccncn3)cc2)n1)C(F)(F)F

InChI Key InChIKey=UUMGJFJGZOIDII-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50219646   

TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219646(CHEMBL247644 | N-(4-(2,3-difluoro-4-(trifluorometh...)
Affinity DataEC50:  87nMAssay Description:Agonist activity at TPO receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219646(CHEMBL247644 | N-(4-(2,3-difluoro-4-(trifluorometh...)
Affinity DataEC50:  87nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed