BDBM50219650 CHEMBL247041::N-(4-(2-fluoro-3-isobutylphenyl)thiazol-2-yl)-4-(pyrimidin-4-ylamino)benzamide

SMILES CC(C)Cc1cccc(-c2csc(NC(=O)c3ccc(Nc4ccncn4)cc3)n2)c1F

InChI Key InChIKey=AVFAUXPMMSGRCW-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219650   

TargetThrombopoietin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50219650(CHEMBL247041 | N-(4-(2-fluoro-3-isobutylphenyl)thi...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at human TPOr expressed in BaF3 cells by reporter assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed