BDBM50220117 (3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-acetylpiperidine-4-carbonyl)-N-methyl-4-phenylpyrrolidine-3-carboxamide::CHEMBL391963

SMILES: CN(Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(=O)[C@H]1CN(C[C@@H]1c1ccccc1)C(=O)C1CCN(CC1)C(C)=O

InChI Key: InChIKey=QOPIOMWNHRCPAA-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50220117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Substance-P receptor (Human)	BDBM50220117 ((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM50220117 ((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Substance-P receptor (Human)	BDBM50220117 ((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
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Substance-P receptor (Human)	BDBM50220117 ((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.420	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM50220117 ((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM50220117 ((3R,4S)-N-(3,5-bis(trifluoromethyl)benzyl)-1-(1-ac...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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