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BDBM50220223 CHEMBL236215::[3-hydroxy-5-(4-trifluoromethyl-benzyloxy)-biphenyl-4-yloxy]-acetic acid

SMILES: OC(=O)COc1c(O)cc(cc1OCc1ccc(cc1)C(F)(F)F)-c1ccccc1

InChI Key: InChIKey=TVGUNUUJRZCCRN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220223   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-tyrosine phosphatase 1B


(Homo sapiens (Human))
BDBM50220223
PNG
(CHEMBL236215 | [3-hydroxy-5-(4-trifluoromethyl-ben...)
Show SMILES OC(=O)COc1c(O)cc(cc1OCc1ccc(cc1)C(F)(F)F)-c1ccccc1
Show InChI InChI=1S/C22H17F3O5/c23-22(24,25)17-8-6-14(7-9-17)12-29-19-11-16(15-4-2-1-3-5-15)10-18(26)21(19)30-13-20(27)28/h1-11,26H,12-13H2,(H,27,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+4n/an/an/an/an/an/a



Inha University

Curated by ChEMBL


Assay Description
Inhibition of PTP1B after 10 mins


Bioorg Med Chem Lett 17: 5357-60 (2007)


Article DOI: 10.1016/j.bmcl.2007.08.019
BindingDB Entry DOI: 10.7270/Q2BK1D55
More data for this
Ligand-Target Pair