BDBM50220311 CHEMBL391108::N-(amino(3-hydroxypropylamino)methylene)-2-(4-(2-chlorophenyl)-2-(2-methyl-4-propoxyphenyl)thiophen-3-yl)acetamide

SMILES CCCOc1ccc(-c2scc(c2CC(=O)NC(=N)NCCCO)-c2ccccc2Cl)c(C)c1

InChI Key InChIKey=WILLYSZDHYQIAN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220311   

TargetBeta-secretase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50220311(CHEMBL391108 | N-(amino(3-hydroxypropylamino)methy...)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of BACE1 by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed