BDBM50220382 4'-methyl-3-trifluoromethyl-biphenyl-4-carbonitrile::CHEMBL392827

SMILES Cc1ccc(cc1)-c1ccc(C#N)c(c1)C(F)(F)F

InChI Key InChIKey=BPHIPLAMILSSMH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220382   

TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220382(4'-methyl-3-trifluoromethyl-biphenyl-4-carbonitril...)
Affinity DataIC50:  200nMAssay Description:Displacement of [3H]-DHT from human recombinant AR expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAndrogen receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50220382(4'-methyl-3-trifluoromethyl-biphenyl-4-carbonitril...)
Affinity DataIC50:  843nMAssay Description:Antagonist activity at human AR in MDA-MB453-MMTV-luci cells by functional assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed