BindingDB logo
myBDB logout

BDBM50220566 CHEMBL172471

SMILES: Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(O)c1ccccn1

InChI Key: InChIKey=FJGCNQALXGWFCZ-UHFFFAOYNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220566   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Peptide N-myristoyltransferase


(Homo sapiens (Human))
BDBM50220566
PNG
(CHEMBL172471)
Show SMILES Cc1c(oc2cccc(OCCCNCc3cccnc3)c12)C(O)c1ccccn1
Show InChI InChI=1/C24H25N3O3/c1-17-22-20(29-14-6-12-26-16-18-7-5-11-25-15-18)9-4-10-21(22)30-24(17)23(28)19-8-2-3-13-27-19/h2-5,7-11,13,15,23,26,28H,6,12,14,16H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 47n/an/an/an/an/an/a



Nippon Roche Research Center

Curated by ChEMBL


Assay Description
Inhibitory activity against Candida albicans Nmt (CaNmt) using substrate peptide GLTISKLFR-R-NH2 (0.5 uM) and myristoyl-CoA (0.5 uM)


Bioorg Med Chem Lett 13: 87-91 (2003)


Article DOI: 10.1016/s0960-894x(02)00844-2
BindingDB Entry DOI: 10.7270/Q25D8V2K
More data for this
Ligand-Target Pair