BDBM50220701 (R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-tert-pentylpiperidin-1-yl)-3-(4-fluorophenyl)-1-oxopropan-2-yl)-4-methylpiperazine-2-carboxamide::CHEMBL268722

SMILES CCC(C)(C)C1(CCN(CC1)C(=O)[C@H](Cc1ccc(F)cc1)NC(=O)[C@H]1CN(C)CCN1)C(=O)NC(C)(C)C

InChI Key InChIKey=NDOKGGMXMSAVRI-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220701   

TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220701((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-tert-penty...)
Affinity DataIC50: 66nMAssay Description:Binding affinity to human MC4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50220701((R)-N-((S)-1-(4-(tert-butylcarbamoyl)-4-tert-penty...)
Affinity DataEC50:  151nMAssay Description:Antagonist activity at human MC4R assessed as stimulation of cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed