BDBM50220960 1-[(3R,3aR)-3-(3-dimethylamino-propyl)-8-fluoro-3-phenyl-3a,4-dihydro-3H-5-oxa-1,9b-diaza-cyclopenta[a]naphthalen-2-yl]-ethanone::CHEMBL250328

SMILES CN(C)CCC[C@]1([C@@H]2COc3ccc(F)cc3N2N=C1C(C)=O)c1ccccc1

InChI Key InChIKey=ZZLRBKFHORVSEX-JTHBVZDNSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220960   

TargetKinesin-like protein KIF11(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220960(1-[(3R,3aR)-3-(3-dimethylamino-propyl)-8-fluoro-3-...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of kinesin spindle proteinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50220960(1-[(3R,3aR)-3-(3-dimethylamino-propyl)-8-fluoro-3-...)
Affinity DataIC50:  5.94E+3nMAssay Description:Inhibition of hERG expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed