BDBM50221044 CHEMBL309253

SMILES Sc1nc(nn1Cc1cccc(Cl)c1)-c1ccccc1Cl

InChI Key InChIKey=BVVNOWWRISDJKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221044   

TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50221044(CHEMBL309253)
Affinity DataIC50: 28nMAssay Description:Inhibition of binding of [125I]IL8 to human recombinant CXC chemokine receptor 2 (CXCR2) expressed in HEK 293 membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 2(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50221044(CHEMBL309253)
Affinity DataIC50: 48nMAssay Description:Antagonist activity at CXCR2 in human neutrophils assessed as reduction in GROalpha stimulated intracellular calcium mobilisation by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed