BDBM50221239 CHEMBL394422::methyl 3-(1-(3-(5-acetyl-3-(4-(trifluoromethyl)phenyl)-4,5,6,7-tetrahydropyrazolo[4,3-c]pyridin-1-yl)-2-hydroxypropyl)piperidin-4-yl)-6-fluorobenzofuran-2-carboxylate

SMILES COC(=O)c1oc2cc(F)ccc2c1C1CCN(CC(O)Cn2nc(c3CN(CCc23)C(C)=O)-c2ccc(cc2)C(F)(F)F)CC1

InChI Key InChIKey=KHQBPFWJMSVKLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221239   

TargetCathepsin S(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50221239(CHEMBL394422 | methyl 3-(1-(3-(5-acetyl-3-(4-(trif...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed