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BDBM50221314 CHEMBL245434::N-butyloxycarbonyl-3-[4-(N-p-tolyl-benzylamidomethyl)phenyl]-5-iso-butylthiophene-2-sulfonamide

SMILES: CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN(C(=O)c2ccccc2)c2ccc(C)cc2)cc1

InChI Key: InChIKey=QDVBDABJANLEDJ-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221314   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AGTR1


(RAT)
BDBM50221314
PNG
(CHEMBL245434 | N-butyloxycarbonyl-3-[4-(N-p-tolyl-...)
Show SMILES CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN(C(=O)c2ccccc2)c2ccc(C)cc2)cc1
Show InChI InChI=1S/C34H38N2O5S2/c1-5-6-20-41-34(38)35-43(39,40)33-31(22-30(42-33)21-24(2)3)27-16-14-26(15-17-27)23-36(29-18-12-25(4)13-19-29)32(37)28-10-8-7-9-11-28/h7-19,22,24H,5-6,20-21,23H2,1-4H3,(H,35,38)
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PC sid
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Similars

Article
PubMed
>1.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]Ang 2 from AT1 receptor in rat liver membranes


Bioorg Med Chem 15: 7166-83 (2007)


Article DOI: 10.1016/j.bmc.2007.07.026
BindingDB Entry DOI: 10.7270/Q2DJ5FBM
More data for this
Ligand-Target Pair