BDBM50221416 22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol(HCl0.5H2O) (Oxymorphindole, OMI)::22-methyl-14-oxa-11,22-diazaheptacyclo[13.9.1.01,13.02,21.04,12.05,10.019,25]pentacosa-4(12),5(10),6,8,15(25),16,18-heptaene-2,16-diol::CHEMBL401093::OXYMORPHINDOLE
SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@]3(O)Cc1c4[nH]c2ccccc12)ccc5O
InChI Key InChIKey=YQNZUKAKYJMEFE-LMDOGRNLSA-N
Data 17 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50221416
Affinity DataKi: 0.700nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of Opioid receptor delta 1More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:The compound was evaluated for binding affinity against Opioid receptor delta 1 in guinea pig brain membrane using [3H]- DPDPE as ligandMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(MOUSE)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Displacement of [3H]DADLE at delta-opioid receptorMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Universit£T Des Saarlandes
Curated by ChEMBL
Universit£T Des Saarlandes
Curated by ChEMBL
Affinity DataKi: 0.800nMAssay Description:Binding affinity to delta opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]p-Cl-DPDPE from delta opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Displacement of [3H]DAMGO at mu-opioid receptorMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Rattus norvegicus (rat))
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 66nMAssay Description:Binding affinity to mu opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
Affinity DataKi: 105nMAssay Description:Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Affinity DataKi: 468nMAssay Description:Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of opioid receptor muMore data for this Ligand-Target Pair
Affinity DataKi: 468nMAssay Description:Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of opioid receptor deltaMore data for this Ligand-Target Pair
Affinity DataKi: 468nMAssay Description:The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligandMore data for this Ligand-Target Pair
Affinity DataKi: 515nMAssay Description:Displacement of [3H]U-69593 from cloned kappa opioid receptorMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
Universit£T Des Saarlandes
Curated by ChEMBL
Universit£T Des Saarlandes
Curated by ChEMBL
Affinity DataKi: 2.17E+3nMAssay Description:Binding affinity to kappa opioid receptor in rat brain membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 4.47E+3nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 4.47E+3nMAssay Description:The compound was evaluated for binding affinity against the opioid receptor kappa in guinea pig brain membranes using [3H]- U-69,593More data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 4.47E+3nMAssay Description:Binding affinity was measured by the displacement of [3H]- EK in guinea pig brain membrane of opioid receptor kappaMore data for this Ligand-Target Pair