BDBM50221535 4-((1R,2S)-2-(2-fluorophenyl)cyclopropylamino)-6,7-dimethoxyquinoline-3-carbonitrile::CHEMBL246419

SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3F)c2cc1OC

InChI Key InChIKey=IRALUWZAVVHHDV-KBXCAEBGSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221535   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Tanabe Research Laboratories Usa

Curated by ChEMBL
LigandPNGBDBM50221535(4-((1R,2S)-2-(2-fluorophenyl)cyclopropylamino)-6,7...)
Affinity DataKi:  36nMAssay Description:Inhibition of human recombinant EGFR by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed