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BDBM50221760 2-(4-methoxyphenyl)-4H-pyrido[1,2-a]pyrimidin-4-one::CHEMBL241976

SMILES: COc1ccc(cc1)-c1cc(=O)n2ccccc2n1

InChI Key: InChIKey=NLFCUULYXAZPBO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50221760   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldose reductase


(Rattus norvegicus)
BDBM50221760
PNG
(2-(4-methoxyphenyl)-4H-pyrido[1,2-a]pyrimidin-4-on...)
Show SMILES COc1ccc(cc1)-c1cc(=O)n2ccccc2n1
Show InChI InChI=1S/C15H12N2O2/c1-19-12-7-5-11(6-8-12)13-10-15(18)17-9-3-2-4-14(17)16-13/h2-10H,1H3
PDB
MMDB

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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Università di Pisa

Curated by ChEMBL


Assay Description
Inhibition of ALR1 in Sprague-Dawley Albino rat kidney


J Med Chem 50: 4917-27 (2007)


Article DOI: 10.1021/jm070398a
BindingDB Entry DOI: 10.7270/Q2TM79TD
More data for this
Ligand-Target Pair