BDBM50221977 (2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)-3-fluoro-pyrrolidin-1-yl)-butan-1-one::(2S,3S)-2-amino-3-(4'-fluorobiphenyl-4-yl)-1-((S)-3-fluoropyrrolidin-1-yl)butan-1-one::CHEMBL237336

SMILES C[C@H]([C@H](N)C(=O)N1CC[C@H](F)C1)c1ccc(cc1)-c1ccc(F)cc1

InChI Key InChIKey=BFIKQYQPKFNDJQ-AGRHKRQWSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50221977   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  8.80E+4nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  64nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  8.60E+4nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 2(Homo sapiens (Human))
Matrix Laboratories Limited

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of QPPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  88nMAssay Description:Inhibition of DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  86nMAssay Description:Inhibition of DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221977((2S,3S)-2-amino-3-(4'-fluoro-biphenyl-4-yl)-1-((S)...)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed