BDBM50221981 (2S,3S)-2-((1s,4R)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)cyclohexyl)-3-amino-4-(3,3-difluoropyrrolidin-1-yl)-N,N-dimethyl-4-oxobutanamide::CHEMBL238191

SMILES CN(C)C(=O)[C@H]([C@H](N)C(=O)N1CCC(F)(F)C1)[C@H]1CC[C@H](CC1)c1ccc2ncnn2c1

InChI Key InChIKey=JNAZOMVWUGPITI-QXGSTGNESA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221981   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221981((2S,3S)-2-((1s,4R)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221981((2S,3S)-2-((1s,4R)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human DPP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221981((2S,3S)-2-((1s,4R)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human DPP4 in presence of 50 % human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 8(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50221981((2S,3S)-2-((1s,4R)-4-([1,2,4]triazolo[1,5-a]pyridi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed