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BDBM50222316 CHEMBL124909

SMILES: ONC(=O)CCCCCCc1nc(cs1)-c1ccccc1

InChI Key: InChIKey=ZCQUIFOQIMJOHM-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222316   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase (HDAC1 and HDAC2)


(Homo sapiens (Human))
BDBM50222316
PNG
(CHEMBL124909)
Show SMILES ONC(=O)CCCCCCc1nc(cs1)-c1ccccc1
Show InChI InChI=1S/C16H20N2O2S/c19-15(18-20)10-6-1-2-7-11-16-17-14(12-21-16)13-8-4-3-5-9-13/h3-5,8-9,12,20H,1-2,6-7,10-11H2,(H,18,19)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against histone deacetylase (HDAC1 and HDAC2) isolated from K562 erythroleukemia cells


Bioorg Med Chem Lett 13: 3817-20 (2003)


Article DOI: 10.1016/j.bmcl.2003.07.012
BindingDB Entry DOI: 10.7270/Q23F4RVV
More data for this
Ligand-Target Pair