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BDBM50222379 CHEMBL129641

SMILES: O=C(CCCCCCOc1ccc(cc1)-c1ccccc1)c1ncc[nH]1

InChI Key: InChIKey=HCGNRZVYDGVQSM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222379   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase


(Homo sapiens (Human))
BDBM50222379
PNG
(CHEMBL129641)
Show SMILES O=C(CCCCCCOc1ccc(cc1)-c1ccccc1)c1ncc[nH]1
Show InChI InChI=1S/C22H24N2O2/c25-21(22-23-15-16-24-22)10-6-1-2-7-17-26-20-13-11-19(12-14-20)18-8-4-3-5-9-18/h3-5,8-9,11-16H,1-2,6-7,10,17H2,(H,23,24)
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibitory activity against Histone deacetylase (HDAC) in K 562 erythroleukemia cells (Radioactivity based HDAC assay)


Bioorg Med Chem Lett 13: 3909-13 (2003)


Article DOI: 10.1016/j.bmcl.2003.09.007
BindingDB Entry DOI: 10.7270/Q2ZP4892
More data for this
Ligand-Target Pair