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BDBM50222686 5-(benzoylamino)-4-bromo-N-(2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)-1H-pyrazole-3-carboxamide::CHEMBL390272

SMILES: Brc1c(NC(=O)c2ccccc2)n[nH]c1C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O

InChI Key: InChIKey=BEPXHHMZTMDGJY-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222686   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))
BDBM50222686
PNG
(5-(benzoylamino)-4-bromo-N-(2,3-dihydro-2-oxo-5-ph...)
Show SMILES Brc1c(NC(=O)c2ccccc2)n[nH]c1C(=O)NC1N=C(c2ccccc2)c2ccccc2NC1=O
Show InChI InChI=1/C26H19BrN6O3/c27-19-21(32-33-22(19)30-24(34)16-11-5-2-6-12-16)25(35)31-23-26(36)28-18-14-8-7-13-17(18)20(29-23)15-9-3-1-4-10-15/h1-14,23H,(H,28,36)(H,31,35)(H2,30,32,33,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 49n/an/an/an/an/an/a



Elan Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor in IL1beta stimulated IMR90 cells by FLIPR assay


J Med Chem 50: 5161-7 (2007)


Article DOI: 10.1021/jm051292n
BindingDB Entry DOI: 10.7270/Q2G73DF9
More data for this
Ligand-Target Pair