BDBM50222709 3,4-difluoro-2-(2-fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)benzamide::CHEMBL244488::PD-0316684::US8575391, 339

SMILES: OCCONC(=O)c1ccc(F)c(F)c1Nc1ccc(I)cc1F

InChI Key: InChIKey=GQAZGSHVSAGDOJ-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50222709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50222709 (CHEMBL244488 | 3,4-difluoro-2-(2-fluoro-4-iodophen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50222709 (CHEMBL244488 | 3,4-difluoro-2-(2-fluoro-4-iodophen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1/2 (Human)	BDBM50222709 (CHEMBL244488 | 3,4-difluoro-2-(2-fluoro-4-iodophen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50222709 (CHEMBL244488 | 3,4-difluoro-2-(2-fluoro-4-iodophen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50222709 (CHEMBL244488 | 3,4-difluoro-2-(2-fluoro-4-iodophen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50222709 (CHEMBL244488 | 3,4-difluoro-2-(2-fluoro-4-iodophen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50222709 (CHEMBL244488 | 3,4-difluoro-2-(2-fluoro-4-iodophen...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair