BDBM50222856 6-(4-chlorophenyl)-3-{[(3S)-1-isopropylpiperidin-3-yl]methyl}-2-methylquinazolin-4(3H)-one::CHEMBL244936

SMILES CC(C)N1CCC[C@H](Cn2c(C)nc3ccc(cc3c2=O)-c2ccc(Cl)cc2)C1

InChI Key InChIKey=ARLXUYKHWSHMLR-SFHVURJKSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50222856   

TargetGrowth hormone secretagogue receptor type 1(Ovis aries)
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50222856(6-(4-chlorophenyl)-3-{[(3S)-1-isopropylpiperidin-3...)
Affinity DataKi:  110nMAssay Description:Displacement of [125I]ghrelin from ovine recombinant GHSR1a expressed in HEK293F cells after 6 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50222856(6-(4-chlorophenyl)-3-{[(3S)-1-isopropylpiperidin-3...)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [125I]DIO from 5HT2c receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bayer Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50222856(6-(4-chlorophenyl)-3-{[(3S)-1-isopropylpiperidin-3...)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed