BDBM50223100 2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido)benzamido)-4-fluoro-3-oxobutanoic acid::CHEMBL237310

SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccccc1C(=O)NC(C(O)=O)C(=O)CF

InChI Key InChIKey=SIQQBFWEHZXLAO-XJDOXCRVSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50223100   

TargetCaspase-6(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human caspase 6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human caspase 7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-1(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human caspase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human recombinant caspase 3 by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-8(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human caspase 8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-9(Homo sapiens (Human))
Epicept

Curated by ChEMBL
LigandPNGBDBM50223100(2-(2-((S)-2-(benzyloxycarbonyl)-3-methylbutanamido...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human caspase 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed