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BDBM50223573 3-bromo-5-cyclopropyl-N-(pyridin-3-ylmethyl)pyrazolo[1,5-a]pyrimidin-7-amine::CHEMBL401056

SMILES: Brc1cnn2c(NCc3cccnc3)cc(nc12)C1CC1

InChI Key: InChIKey=TWEBALJIBJFYCZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223573   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))
BDBM50223573
PNG
(3-bromo-5-cyclopropyl-N-(pyridin-3-ylmethyl)pyrazo...)
Show SMILES Brc1cnn2c(NCc3cccnc3)cc(nc12)C1CC1
Show InChI InChI=1S/C15H14BrN5/c16-12-9-19-21-14(18-8-10-2-1-5-17-7-10)6-13(11-3-4-11)20-15(12)21/h1-2,5-7,9,11,18H,3-4,8H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.13E+3n/an/an/an/an/an/a



Schering-Plough Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human GSK3beta


Bioorg Med Chem Lett 17: 6220-3 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.017
BindingDB Entry DOI: 10.7270/Q27M07ND
More data for this
Ligand-Target Pair